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15-night Grand Ohio River Cruise

Pittsburgh/St. Louis

Voyage Overview

Embarkation
Pittsburgh
Disembarkation
St. Louis
Destination Highlight

Pittsburgh's landscape is a rolling prairie filled with beautiful trees that change color with each season. Along with the majestic beauty Pittsburgh has fun festivals, arts and crafts, shopping, golf, spectator sports, fine dining, museums, great outdoor activities and so much more. Pittsburgh offers a range of culture and arts typically found in cities twice its size, while maintaining the safety and accessibility of a small town. A few of Pittsburgh's favorite family things include: The Carnagie Science Center, Pittsburgh Zoo, and Kennywood Park. There are many more attractions and activities sure to please any age group, whether it's a seven-year old visiting Mr. Roger's Neighborhood of Make Believe at Idlewild Park or a teenager bent on what's undeniably cool as she walks on the wild side through The Andy Warhol Museum.

About the Ship
The Future of American River Cruising™ continues with American Melody, the 4th in the modern riverboat series. American Melody showcases a whole new aesthetic, with an updated interior design, bringing ship to the next level of modern sophistication. Specifically designed to navigate the Mississippi River, American Melody features panoramic views throughout, including an impressive four-story glass atrium in the center of the ship. Ranging from 250 to 650 square feet, all of the spacious staterooms feature full-size bathrooms, roomy closets, and private balconies where you can enjoy daily breakfast room service. American Melody also offers the Ellipse Café for casual dining, an option that has been very popular with the guests.

Daily Itinerary
Sep 10, 2028 - Pittsburgh

Pittsburgh's landscape is a rolling prairie filled with beautiful trees that change color with each season. Along with the majestic beauty Pittsburgh has fun festivals, arts and crafts, shopping, golf, spectator sports, fine dining, museums, great outdoor activities and so much more. Pittsburgh offers a range of culture and arts typically found in cities twice its size, while maintaining the safety and accessibility of a small town. A few of Pittsburgh's favorite family things include: The Carnagie Science Center, Pittsburgh Zoo, and Kennywood Park. There are many more attractions and activities sure to please any age group, whether it's a seven-year old visiting Mr. Roger's Neighborhood of Make Believe at Idlewild Park or a teenager bent on what's undeniably cool as she walks on the wild side through The Andy Warhol Museum.

Sep 11, 2028 - Pittsburgh

Pittsburgh's landscape is a rolling prairie filled with beautiful trees that change color with each season. Along with the majestic beauty Pittsburgh has fun festivals, arts and crafts, shopping, golf, spectator sports, fine dining, museums, great outdoor activities and so much more. Pittsburgh offers a range of culture and arts typically found in cities twice its size, while maintaining the safety and accessibility of a small town. A few of Pittsburgh's favorite family things include: The Carnagie Science Center, Pittsburgh Zoo, and Kennywood Park. There are many more attractions and activities sure to please any age group, whether it's a seven-year old visiting Mr. Roger's Neighborhood of Make Believe at Idlewild Park or a teenager bent on what's undeniably cool as she walks on the wild side through The Andy Warhol Museum.

Sep 12, 2028 - River Cruising

Relax and enjoy your day as you cruise along the river and take in the magnificent scenery.

Sep 13, 2028 - Marietta

Visitors have the chance to discover the rich history and heritage of this charming city by visiting museums, landmarks, and craft artists as they show you century-old techniques. Marietta also has a huge shopping culture as you will find out when you stop in at the many unique boutiques, antique stores, galleries, and confectionery stores. If you are looking for a relaxing activity then taking a quiet river cruise is an excellent way to enjoy the scenery of this beautiful city.

Sep 14, 2028 - River Cruising

Relax and enjoy your day as you cruise along the river and take in the magnificent scenery.

Sep 15, 2028 - Maysville

Maysville is a wonderful getaway destination that offers something for everyone. Maysville-Mason park is an excellent place to take in the beautiful kentucky scenery while enjoying the par-three gold course, 12-acre fishing lake, walking trail, and olympic size swimming pool.  Maysville is also a popular location for ATV and dirt bike trail riding.  Surrounded by beautiful green pasture, visitors are invited to visit a farm and learn about how people lived in during colonial times.

Sep 16, 2028 - Cincinnati

Cincinnati has a variety of attractions, fine dining and shopping, and family activities that are sure to please everyone. The Cincinnati Museum Center at Union Terminal offers five great museum in one historic location, and has an amazing collection of dinosaurs. For nature lovers there is the Cincinnati Zoo, Botanical Gardens, and Loveland Bike Trail. Visitors can discover the hundreds of festivals and one-of-a-kind events in Cincinnati, from culinary treats to major music festivals, the region is abuzz with activity all year long.

Sep 17, 2028 - Madison

Madison is a beautiful historic town on the Ohio River in Indianapolis. There are many beautiful historic buildings and  landmarks to explore including the Francis Costigan House, and Madison Railroad Station. Outdoor lovers will enjoy a visit to the Clifty Falls State Park which features, waterfalls, rock gorges, and lush green scenic overlooks.

Sep 18, 2028 - Louisville

Louisville is the largest city in Kentucky and an industrial, financial, marketing, and shipping center of the South. The city has some of the nation's largest whiskey distilleries and cigarette factories. Louisville developed as a portage place around the falls and as a river port and major commercial center. Many of the nation's most famous steamboats were constructed there. Churchill Downs, a noted racetrack, is scene of the annual Kentucky Derby. The city has noted parks and is site of the state fairgrounds. It has a symphony orchestra and an opera company and hosts an annual festival of new American plays. Among points of interest are American Printing House for the Blind; J.B. Speed Art Museum; Kentucky Center for the Arts; Actors Theater of Louisville; “Farmington”; Filson Club, with a historical library and museum; Jefferson County Courthouse; and Cave Hill Cemetery, where Clark is buried. Nearby is “Locust Grove,” the last home of Clark, as well as the burial place of Zachary Taylor. Fort Knox is in the area.

Sep 19, 2028 - River Cruising

Relax and enjoy your day as you cruise along the river and take in the magnificent scenery.

Sep 20, 2028 - Henderson

Henderson lies along the beautiful Ohio River, and offers a beautiful riverfront, great southern food, and friendly hospitality. Before prohibition, Kentucky had the largest number of vineyards in the U.S. and reviving this tradition Henderson invited visitors to enjoy wine tasting at a number of wineries, including Ruby Moon Winery.  In June the W.C. andy Blues & Barbecue Festival offers excellent food and entertainment by some nationally know artists, as does the the Bluegrass in the Park & Folklife Festival.

Sep 20, 2028 - Evansville

Many eras of Midwestern history are on display in the southwest Indiana town of Evansville. Remnants of ancient residents are on view at Angel Mounds State Historic site, which features interactive exhibits about the people of the Middle Mississippian culture who inhabited this area 1100-1450.

Just across the river in Henderson, Kentucky, is the John J. Audubon Center; the naturalist and artist lived in the area 1810-19. Evansville Museum Transportation Center details the history of early river, rail, aviation and street transportation and includes a steam engine, club car and caboose from the early 1900s.

Downtown Evansville is also home to Tropicana Casino and its neighboring entertainment complex, which is filled with restaurants, nightclubs and other attractions.

The Ellis Park racetrack is just minutes from downtown Evansville in Henderson, Kentucky. Built in 1922 and owned by Churchill Downs, the track features Thoroughbred races several days a week July through Labor Day.

Sep 21, 2028 - River Cruising

Relax and enjoy your day as you cruise along the river and take in the magnificent scenery.

Sep 22, 2028 - Paducah

Paducah is a thriving, artistic city on the banks of the Ohio River. The city supports its artisans through incentive programs, offering the opportunity to create a truly unique community. Along the riverfront, the Market District hosts many opportunities for dining, shopping and museum going. You can also see giant murals along 2nd Street, painted by Robert Dafford. In the Lowertown Art District, visit a plethora of art galleries, independent coffee houses and unique "fusion" dining. For a look at the region's crafts, visit the William Clark Market House Mueum or the annual Quilt Show, which occurrs every April. Every May, Lowertown hosts a fine art and music festival, highlighting local artists and musicians in a lively, all day event.

Sep 23, 2028 - River Cruising

Relax and enjoy your day as you cruise along the river and take in the magnificent scenery.

Sep 24, 2028 - St. Louis

St. Louis's "gateway to the west", the Gateway Arch, is a nationally recognized site as it stands over 630 feet above the Mississippi River. Although the arch is a great site, visit some other St. Louis attractions including: historic landmarks, museums, sightseeing, shopping, and accommodations to fit every budget. St. Louis has attractions and activities for a family on vacation, someone visiting for business, or a couple searching for romance. Boating tours, museums, historic sites such as the village where Daniel Boon lived, shopping, fine dinging, and educational attractions are all within minutes from anywhere in the city. St. Louis offers culture, sophistication, old world charm, and fantastic architecture.

Sep 25, 2028 - St. Louis

St. Louis's "gateway to the west", the Gateway Arch, is a nationally recognized site as it stands over 630 feet above the Mississippi River. Although the arch is a great site, visit some other St. Louis attractions including: historic landmarks, museums, sightseeing, shopping, and accommodations to fit every budget. St. Louis has attractions and activities for a family on vacation, someone visiting for business, or a couple searching for romance. Boating tours, museums, historic sites such as the village where Daniel Boon lived, shopping, fine dinging, and educational attractions are all within minutes from anywhere in the city. St. Louis offers culture, sophistication, old world charm, and fantastic architecture.

Stateroom Options

Grand Suite
Grand Suite (Cat Grand)
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Suite size: 650 sq ft. The Grand Suites are the finest shipboard accommodations on any small cruise ship, featuring a living room, bedroom, dining table and breakfast bar, balcony and a spacious master bathroom, floor-to-ceiling sliding doors in both the bedroom and living room leading to a 25-foot-long private balcony with table, chairs and chaise lounge, living room with TV, dining area with coffee machine and refrigerator restocked daily, bedroom with additional TV and king-size bed convertible to two twin beds, bathroom with double vanity and large shower, toiletries, hairdryer, plush towels and robes, storage with wardrobe, full-size dresser and desk drawers, plus individual climate control, safe and USB charging ports.

Veranda Suite
Veranda Suite (Cat Veranda)
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Suite size: 405 sq ft. Features floor-to-ceiling glass doors leading to a private balcony with table and chairs, king-size bed convertible to two twin beds, full bathroom with large shower, toiletries, hairdryer and plush towels, storage with wardrobe, full-size dresser, under-bed storage and desk drawers, plus individual climate control, TV, safe and USB charging ports.

Premium Balcony Stateroom
Premium Balcony Stateroom (Cat Premium)
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Stateroom size: 350 sq ft. Features floor-to-ceiling glass doors leading to a private balcony with table and chairs, king-size bed convertible to two twin beds, full bathroom with large shower, toiletries, hairdryer and plush towels, storage with wardrobe, full-size dresser, under-bed storage and desk drawers, plus individual climate control, TV, safe and USB charging ports.

Deluxe Balcony Stateroom
Deluxe Balcony Stateroom (Cat Deluxe)
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Stateroom size: 315 sq ft. Features floor-to-ceiling glass doors leading to a private balcony with table and chairs, king-size bed convertible to two twin beds, full bathroom with large shower, toiletries, hairdryer and plush towels, storage with wardrobe, full-size dresser, under-bed storage and desk drawers, plus individual climate control, TV, safe and USB charging ports.

Standard Balcony Stateroom
Standard Balcony Stateroom (Cat Standard)
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Stateroom size: 275 sq ft. Features floor-to-ceiling glass doors leading to a private balcony with table and chairs, king-size bed convertible to two twin beds, full bathroom with large shower, toiletries, hairdryer and plush towels, storage with wardrobe, full-size dresser, under-bed storage and desk drawers, plus individual climate control, TV, safe and USB charging ports.

Single Balcony Stateroom
Single Balcony Stateroom (Cat Single)
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Stateroom size: 250 sq ft. Includes a floor-to-ceiling glass door leading to a full-size private balcony with table and chairs, full-size bed, full bathroom with large shower, toiletries, hairdryer and plush towels, storage with wardrobe, full-size dresser, under-bed storage and desk drawers, plus individual climate control, TV, safe and USB charging ports.

Included Amenities

Exclusive Bonus:
  • $100 per Couple Shipboard Credit
  • Cruise
  • Meals
  • Entertainment and more

Additional Departure Dates for This Itinerary

Select an upcoming departure below to view availability or lock in exclusive Signature Travel Network perks.

Jul 02, 2027
15-night Grand Ohio River Cruise
15 Nights • American Melody • St. Louis/Pittsburgh
Signature PerksSpecial Rate
Jul 16, 2027
15-night Grand Ohio River Cruise
15 Nights • American Melody • Pittsburgh/St. Louis
Signature PerksSpecial Rate
Aug 11, 2028
15-night Grand Ohio River Cruise
15 Nights • American Melody • St. Louis/Pittsburgh
Signature PerksSpecial Rate

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Fares listed are per person, based on double occupancy and include all gratuities, port charges and fees.

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Trip Summary
Ship Name American Melody
Departure Date September 10, 2028
Duration 15 Nights
Offer ID 1710047
Ship Facts
Built 2021
Guests 182
Crew 50
Call Vincent Vacations: 1 (888) 883-0460
Prices are per person based on double occupancy. Pricing on some sailings may reflect special limited time offers, not combinable with any other offers/discounts. Valid on new bookings only. American Cruise Lines includes all shipboard meals, entertainment, tips and gratuities, alcohol, and other port charges and fees in the price of the cruise. Many shore excursions are also included in the cost of the cruise.

All fares are quoted in US Dollars.