Central America Cruises: 69 Sailings, Top Ships & Deals

PORT-BY-PORT SCHEDULES

Central America Cruise Itineraries (55 Shown)

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14 NightsDisney Cruise Line Disney Magic

14-Night 14-Night Eastbound Panama Canal Cruise From San Diego Ending In Galveston

Embark: San Diego → Debark: Galveston â€¢ Region: Central America

1 Available Departures â€¢ Next Sailing: Nov 06, 2026

Fares Starting From$2,477per person, double occupancy

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17 NightsViking Expeditions Viking Octantis

17-Night Panama & Scenic South America

Embark: Ft Lauderdale (Port Everglades) → Debark: Valparaiso â€¢ Region: South America

1 Available Departures â€¢ Next Sailing: Nov 06, 2026

Fares Starting From$9,299per person, double occupancy

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14 NightsViking Ocean Viking Mars

14-Night Panama Canal & Central America

Embark: Ft Lauderdale (Port Everglades) → Debark: Ft Lauderdale (Port Everglades) â€¢ Region: Caribbean

6 Available Departures â€¢ Next Sailing: Nov 23, 2026

Fares Starting From$5,999per person, double occupancy

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11 NightsWindstar Wind Star

11-Night Colombian & Southern Caribbean Coastlines

Embark: Bridgetown → Debark: Colon â€¢ Region: Caribbean

1 Available Departures â€¢ Next Sailing: Nov 24, 2026

Fares Starting From$5,036per person, double occupancy

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16 NightsWindstar Star Legend

16-Night Star Collector: Windward Islands & Spanish New World

Embark: Bridgetown → Debark: Balboa â€¢ Region: Central America

1 Available Departures â€¢ Next Sailing: Dec 04, 2026

Fares Starting From$5,742per person, double occupancy

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12 NightsSeabourn Seabourn Quest

12-Night 12-Day World Cruise: Panama Canal To Callao

Embark: Miami → Debark: Callao â€¢ Region: South America

1 Available Departures â€¢ Next Sailing: Jan 05, 2027

Fares Starting From$7,238per person, double occupancy

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35 NightsSeabourn Seabourn Quest

35-Night 35-Day World Cruise: Panama Canal Crossing & Polynesia

Embark: Miami → Debark: Papeete â€¢ Region: South America

1 Available Departures â€¢ Next Sailing: Jan 05, 2027

Fares Starting From$17,098per person, double occupancy

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31 NightsCrystal Crystal Serenity

31-Night Transoceanic

Embark: San Diego → Debark: Papeete â€¢ Region: South Pacific

1 Available Departures â€¢ Next Sailing: Jan 08, 2027

Fares Starting From$17,600per person, double occupancy

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14 NightsViking Ocean Viking Mars

14-Night Panama Canal & Central America

Embark: Ft Lauderdale (Port Everglades) → Debark: Ft Lauderdale (Port Everglades) â€¢ Region: Caribbean

1 Available Departures â€¢ Next Sailing: Jan 10, 2027

Fares Starting From$8,499per person, double occupancy

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12 NightsWindstar Star Legend

12-Night Costa Rica, Panama & Machu Picchu Cruise Tour

Embark: Puntarenas → Debark: Lima â€¢ Region: South America

1 Available Departures â€¢ Next Sailing: Jan 26, 2027

Fares Starting From$8,243per person, double occupancy

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14 NightsWindstar Star Legend

14-Night Star Collector: Windward Islands & Spanish New World

Embark: Balboa → Debark: Bridgetown â€¢ Region: Central America

1 Available Departures â€¢ Next Sailing: Feb 16, 2027

Fares Starting From$10,962per person, double occupancy

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14 NightsCunard Queen Anne

14-Night Fort Lauderdale To Southampton

Embark: Ft Lauderdale (Port Everglades) → Debark: Southampton â€¢ Region: Europe

1 Available Departures â€¢ Next Sailing: Mar 19, 2027

Fares Starting From$1,099per person, double occupancy

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16 NightsHolland America Oosterdam

16-Night 16-Day Inca & Panama Canal Discovery: Lima Overnight

Embark: Santiago → Debark: Ft Lauderdale (Port Everglades) â€¢ Region: Caribbean

1 Available Departures â€¢ Next Sailing: Mar 24, 2027

Fares Starting From$2,299per person, double occupancy

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16 NightsVirgin Voyages Brilliant Lady

16-Night Panama Canal: Miami To Los Angeles

Embark: Miami → Debark: Los Angeles â€¢ Region: Panama Canal

2 Available Departures â€¢ Next Sailing: Mar 26, 2027

Fares Starting From$2,064per person, double occupancy

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29 NightsMSC Cruises MSC Poesia

29-Night MSC Grand Voyages, 29 Nights

Embark: Miami → Debark: Seattle â€¢ Region: Pacific Coastal

1 Available Departures â€¢ Next Sailing: Mar 28, 2027

Fares Starting From$2,829per person, double occupancy

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11 NightsScenic Luxury Cruises & Tours Scenic Eclipse II

11-Night Pristine Islands Of The Caribbean & The Panama Canal

Embark: Panama City → Debark: Bridgetown â€¢ Region: Central America

1 Available Departures â€¢ Next Sailing: Apr 03, 2027

Fares Starting From$10,089per person, double occupancy

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5 NightsDisney Cruise Line Disney Wonder

5-Night 5-Night Baja Cruise From San Diego

Embark: San Diego → Debark: San Diego â€¢ Region: Central America

1 Available Departures â€¢ Next Sailing: Apr 14, 2027

Fares Starting From$1,257per person, double occupancy

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46 NightsSeabourn Seabourn Quest

46-Night 46-Day World Cruise: South Pacific & Panama Canal

Embark: Brisbane → Debark: Miami â€¢ Region: Hawaii

1 Available Departures â€¢ Next Sailing: Apr 15, 2027

Fares Starting From$19,098per person, double occupancy

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14 NightsDisney Cruise Line Disney Magic

14-Night 14-Night Westbound Panama Canal Cruise From Galveston Ending In San Diego

Embark: Galveston → Debark: San Diego â€¢ Region: Central America

1 Available Departures â€¢ Next Sailing: Apr 25, 2027

Fares Starting From$3,011per person, double occupancy

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31 NightsSeabourn Seabourn Quest

31-Night 31-Day Panama Canal & Atlantic Passage

Embark: Long Beach → Debark: Lisbon â€¢ Region: Mexico

1 Available Departures â€¢ Next Sailing: May 11, 2027

Fares Starting From$20,098per person, double occupancy

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19 NightsMSC Cruises MSC Poesia

19-Night MSC Grand Voyages, 19 Nights

Embark: Seattle → Debark: Miami â€¢ Region: Caribbean

1 Available Departures â€¢ Next Sailing: Sep 27, 2027

Fares Starting From$1,989per person, double occupancy

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21 NightsHolland America Nieuw Amsterdam

21-Night 21-Day Inca Coast Discovery Segment

Embark: San Diego → Debark: Santiago â€¢ Region: Mexico

1 Available Departures â€¢ Next Sailing: Oct 12, 2027

Fares Starting From$2,954per person, double occupancy

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36 NightsHolland America Nieuw Amsterdam

36-Night 36-Day Inca Coast Discovery Collectors' Voyage

Embark: San Diego → Debark: Buenos Aires â€¢ Region: Mexico

1 Available Departures â€¢ Next Sailing: Oct 12, 2027

Fares Starting From$4,504per person, double occupancy

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11 NightsScenic Luxury Cruises & Tours Scenic Eclipse

11-Night Pristine Islands Of The Caribbean & The Panama Canal

Embark: Bridgetown → Debark: Panama City â€¢ Region: Central America

1 Available Departures â€¢ Next Sailing: Oct 20, 2027

Fares Starting From$9,863per person, double occupancy

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59 NightsOceania Cruises Oceania Vista

59-Night Bound For Down Under

Embark: Miami → Debark: Sydney â€¢ Region: Caribbean

1 Available Departures â€¢ Next Sailing: Oct 24, 2027

Fares Starting From$26,399per person, double occupancy

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14 NightsDisney Cruise Line Disney Magic

14-Night 14-Night Eastbound Panama Canal Cruise From San Diego Ending In Galveston

Embark: San Diego → Debark: Galveston â€¢ Region: Central America

1 Available Departures â€¢ Next Sailing: Nov 04, 2027

Fares Starting From$2,701per person, double occupancy

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14 NightsViking Ocean Viking Mars

14-Night Panama Canal & Central America

Embark: Ft Lauderdale (Port Everglades) → Debark: Ft Lauderdale (Port Everglades) â€¢ Region: Caribbean

5 Available Departures â€¢ Next Sailing: Nov 05, 2027

Fares Starting From$5,099per person, double occupancy

Dates & Day-by-Day Book Online →

21 NightsWindstar Star Pride

21-Night Star Collector: Windward Islands, Spanish Cities & Costa Rica

Embark: San Juan → Debark: Puntarenas â€¢ Region: Caribbean

1 Available Departures â€¢ Next Sailing: Nov 22, 2027

Fares Starting From$7,565per person, double occupancy

Dates & Day-by-Day Book Online →

17 NightsVirgin Voyages Brilliant Lady

17-Night Panama Canal: Los Angeles To Miami

Embark: Los Angeles → Debark: Miami â€¢ Region: South America

1 Available Departures â€¢ Next Sailing: Nov 27, 2027

Fares Starting From$1,854per person, double occupancy

Dates & Day-by-Day Book Online →

14 NightsWindstar Star Pride

14-Night Star Collector: Coffee, Canal & Callaloo: Central America, Columbia & The Caribbean

Embark: San Juan → Debark: Puntarenas â€¢ Region: Caribbean

1 Available Departures â€¢ Next Sailing: Nov 29, 2027

Fares Starting From$5,434per person, double occupancy

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25 NightsEmerald Cruises Emerald Azzurra

25-Night Epic Caribbean Escape: Barbados To Costa Rica

Embark: Bridgetown → Debark: San Jose â€¢ Region: Central America

1 Available Departures â€¢ Next Sailing: Jan 06, 2028

Fares Starting From$22,284per person, double occupancy

Dates & Day-by-Day Book Online →

57 NightsSeabourn Seabourn Quest

57-Night 57-Day Panama Canal, Chilean Fjords, Antarctica & Falklands

Embark: Miami → Debark: Buenos Aires â€¢ Region: South America

1 Available Departures â€¢ Next Sailing: Jan 07, 2028

Fares Starting From$36,998per person, double occupancy

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11 NightsEmerald Cruises Emerald Azzurra

11-Night Grenadines, Colombia & Panama Canal Transit

Embark: Bridgetown → Debark: Panama City â€¢ Region: Central America

2 Available Departures â€¢ Next Sailing: Jan 13, 2028

Fares Starting From$10,296per person, double occupancy

Dates & Day-by-Day Book Online →

33 NightsSilversea Silver Ray

33-Night 33 Night South America Voyage

Embark: Miami → Debark: Buenos Aires â€¢ Region: South America

1 Available Departures â€¢ Next Sailing: Jan 15, 2028

Fares Starting From$24,200per person, double occupancy

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7 NightsEmerald Cruises Emerald Azzurra

7-Night Coastal Adventures: Panama & Costa Rica

Embark: Panama City → Debark: San Jose â€¢ Region: Central America

2 Available Departures â€¢ Next Sailing: Jan 24, 2028

Fares Starting From$5,460per person, double occupancy

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12 NightsEmerald Cruises Emerald Azzurra

12-Night Costa Rica, Panama From The Pacific To The Atlantic Via The Panama Canal

Embark: San Jose → Debark: San Jose â€¢ Region: Central America

1 Available Departures â€¢ Next Sailing: Feb 10, 2028

Fares Starting From$10,551per person, double occupancy

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7 NightsEmerald Cruises Emerald Azzurra

7-Night Coastal Adventures: Costa Rica & Panama

Embark: San Jose → Debark: Panama City â€¢ Region: Central America

2 Available Departures â€¢ Next Sailing: Feb 22, 2028

Fares Starting From$5,310per person, double occupancy

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11 NightsEmerald Cruises Emerald Azzurra

11-Night Panama Canal Transit, Colombia & The Grenadines

Embark: Panama City → Debark: Bridgetown â€¢ Region: Central America

2 Available Departures â€¢ Next Sailing: Feb 29, 2028

Fares Starting From$10,296per person, double occupancy

Dates & Day-by-Day Book Online →

17 NightsHolland America Nieuw Amsterdam

17-Night 17-Day Inca & Panama Canal Discovery: Lima Overnight

Embark: Santiago → Debark: Ft Lauderdale (Port Everglades) â€¢ Region: Caribbean

1 Available Departures â€¢ Next Sailing: Mar 21, 2028

Fares Starting From$2,894per person, double occupancy

Dates & Day-by-Day Book Online →

14 NightsDisney Cruise Line Disney Magic

14-Night 14-Night Westbound Panama Canal Cruise From Galveston Ending In San Diego

Embark: Galveston → Debark: San Diego â€¢ Region: Central America

1 Available Departures â€¢ Next Sailing: Mar 26, 2028

Fares Starting From$2,629per person, double occupancy

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16 NightsSeabourn Seabourn Pursuit

16-Night 16-Day Panama Canal & Historic Coasts Of South America

Embark: Aruba → Debark: Valparaiso â€¢ Region: South America

1 Available Departures â€¢ Next Sailing: Oct 02, 2028

Fares Starting From$10,998per person, double occupancy

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11 NightsScenic Luxury Cruises & Tours Scenic Eclipse

11-Night Voyage Of The Tropics: Bahamas, Caribbean & Panama Canal

Embark: Miami → Debark: Panama City â€¢ Region: Central America

1 Available Departures â€¢ Next Sailing: Oct 13, 2028

Fares Starting From$9,683per person, double occupancy

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38 NightsSeabourn Seabourn Quest

38-Night 38-Day Amazon Explorer & Caribbean Shores

Embark: Miami → Debark: Miami â€¢ Region: Caribbean

1 Available Departures â€¢ Next Sailing: Nov 10, 2028

Fares Starting From$19,799per person, double occupancy

Dates & Day-by-Day Book Online →

30 NightsSeabourn Seabourn Quest

30-Night 30-Day Amazon Explorer: Rivers & Rainforests

Embark: Miami → Debark: Miami â€¢ Region: Caribbean

1 Available Departures â€¢ Next Sailing: Nov 18, 2028

Fares Starting From$16,999per person, double occupancy

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40 NightsSeabourn Seabourn Quest

40-Night 40-Day Amazon Explorer & Caribbean Discovery

Embark: Miami → Debark: Miami â€¢ Region: Caribbean

1 Available Departures â€¢ Next Sailing: Nov 18, 2028

Fares Starting From$21,899per person, double occupancy

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13 NightsSeabourn Seabourn Quest

13-Night 13-Day World Cruise: Panama Canal & South American Explorer

Embark: Miami → Debark: Callao â€¢ Region: South America

1 Available Departures â€¢ Next Sailing: Jan 07, 2029

Fares Starting From$8,099per person, double occupancy

Dates & Day-by-Day Book Online →

30 NightsSeabourn Seabourn Quest

30-Night 30-Day World Cruise: South America To French Polynesia

Embark: Miami → Debark: Papeete â€¢ Region: South America

1 Available Departures â€¢ Next Sailing: Jan 07, 2029

Fares Starting From$16,799per person, double occupancy

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58 NightsSeabourn Seabourn Quest

58-Night 58-Day World Cruise: South America & South Pacific Discovery

Embark: Miami → Debark: Sydney â€¢ Region: South America

1 Available Departures â€¢ Next Sailing: Jan 07, 2029

Fares Starting From$32,399per person, double occupancy

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12 NightsEmerald Cruises Emerald Azzurra

12-Night Costa Rica, Panama From The Atlantic To The Pacific Via The Panama Canal

Embark: San Jose → Debark: San Jose â€¢ Region: Central America

1 Available Departures â€¢ Next Sailing: Jan 31, 2029

Fares Starting From$10,847per person, double occupancy

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12 NightsEmerald Cruises Emerald Azzurra

12-Night Costa Rica, Panama From The Pacific To The Atlantic Via The Panama Canal

Embark: San Jose → Debark: San Jose â€¢ Region: Central America

1 Available Departures â€¢ Next Sailing: Feb 10, 2029

Fares Starting From$10,899per person, double occupancy

Dates & Day-by-Day Book Online →

31 NightsHolland America Oosterdam

31-Night 31-Day Panama Canal, Inca & South America: Chilean Fjords

Embark: Ft Lauderdale (Port Everglades) → Debark: Buenos Aires â€¢ Region: Caribbean

1 Available Departures â€¢ Next Sailing: Nov 18, 2026

Fares Starting FromCall for Exclusive Rateper person, double occupancy

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16 NightsHolland America Oosterdam

16-Night 16-Day Inca & Panama Canal Discovery: Lima Overnight

Embark: Ft Lauderdale (Port Everglades) → Debark: Valparaiso â€¢ Region: Caribbean

1 Available Departures â€¢ Next Sailing: Nov 18, 2026

Fares Starting FromCall for Exclusive Rateper person, double occupancy

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62 NightsSeabourn Seabourn Quest

62-Night 62-Day World Cruise: Panama Canal, Polynesia & New Zealand

Embark: Miami → Debark: Sydney â€¢ Region: South America

1 Available Departures â€¢ Next Sailing: Jan 05, 2027

Fares Starting FromCall for Exclusive Rateper person, double occupancy

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145 NightsSeabourn Seabourn Quest

145-Night 145-Day World Cruise: Australia & South Pacific Panorama

Embark: Miami → Debark: Miami â€¢ Region: Caribbean

1 Available Departures â€¢ Next Sailing: Jan 05, 2027

Fares Starting FromCall for Exclusive Rateper person, double occupancy

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126 NightsSeabourn Seabourn Quest

126-Night 126-Day World Cruise: Australia & South Pacific Panorama

Embark: Miami → Debark: Long Beach â€¢ Region: South America

1 Available Departures â€¢ Next Sailing: Jan 05, 2027

Fares Starting FromCall for Exclusive Rateper person, double occupancy

Dates & Day-by-Day Book Online →

Central America Cruises & Itineraries

Top Cruise Lines in Central America

Top Departure Ports for Central America

Central America Cruise Itineraries (55 Shown)