VINCENT VACATIONS
21-NIGHT CRUISE SPECIALS | PANAMA CANAL

21-Night Panama Canal Cruises & Sailing Dates

Compare 3 upcoming sailings and 3 unique itineraries for 21-night voyages to Panama Canal starting from $2,099 per person.

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All Cruises Hub 34 Cruise Lines 450+ Cruise Ships 76 Destinations 293 Departure Ports Top Deals & Onboard Credit
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LEADING FLEETS

Top Cruise Lines in Panama Canal

Princess (48 sailings)Norwegian Cruise Line (37 sailings)Windstar (30 sailings)Oceania Cruises (24 sailings)Holland America (20 sailings)Regent Seven Seas (18 sailings)Viking Ocean (15 sailings)Celebrity Cruises (8 sailings)Seabourn (8 sailings)Viking Expeditions (7 sailings)Cunard (4 sailings)Carnival Cruise Line (4 sailings)
EMBARKATION CITIES

Top Departure Ports for Panama Canal

Ft Lauderdale (Port Everglades) (59 departures)Miami (59 departures)Los Angeles (25 departures)Panama City (15 departures)Colon (13 departures)Puntarenas (12 departures)New York City (11 departures)San Diego (8 departures)Reykjavik (6 departures)Tampa (4 departures)Vancouver (4 departures)Balboa (3 departures)
PORT-BY-PORT SCHEDULES

21-Night Panama Canal Cruise Itineraries (3 Shown)

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21 NightsHolland AmericaEurodam🎁 Save on Sunshine - Up to 50% Off!

21-Night 21-Day Panama Canal

Embark: Ft Lauderdale (Port Everglades) → Debark: Seattle • Region: Panama Canal

Ports of Call: Ft Lauderdale (Port Everglades) • Cartagena • Cristobal • Panama Canal • Balboa • Puntarenas

1 Available Departures • Next Sailing: Apr 03, 2027

Fares Starting From$2,199Balcony from $3,799 • Suite from $6,699
Dates & Day-by-DayGet Quote & Perks →
THE SIGNATURE TRAVEL NETWORK ADVANTAGE

Why Book 21-Night Panama Canal Cruises with Vincent Vacations Instead of Direct?

You pay the exact same promotional cruise line rate with $0 agency booking fees, while unlocking exclusive consortium perks unavailable on retail websites:

✓ $100–$600+ Shipboard Credits✓ Private Car & Driver Shore Excursions✓ Hosted Voyages & VIP Receptions✓ 100% Loyalty Points + Promo Stacking✓ Price-Drop Monitoring Before Final Payment
Request Custom Quote & Perks →Call 1-888-883-0460Already booked direct within 60 days? Ask about our complimentary perk transfer.
EXPERT CRUISE GUIDANCE

Frequently Asked Questions About 21-Night Panama Canal Cruises

How much does a 21-night Panama Canal cruise cost?

We currently track 3 21-night Panama Canal sailings across 3 itineraries, with stateroom fares starting from $2,099 per person before taxes and port fees.

How do I get extra onboard credit on a 21-night Panama Canal cruise?

Request a custom quote on this page or call 1-888-883-0460. Our certified cruise advisors match all promotional fares and attach exclusive Signature Travel Network perks ($100-$600+ shipboard credit) on eligible 21-night Panama Canal voyages.

Which cruise lines offer 21-night Panama Canal voyages?

Browse the complete fleet of 21-night itineraries below to compare lines, ships, and departure dates sailing Panama Canal.

Signature Travel Network Perks: Up to $600 Shipboard Credit + Price-Match Guarantee + $0 Booking Fees
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